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                    GCSE AQA Biology Topic 3: Infection and Response
                    
                 
                    
        
        
            
    
        
                                    This is a draft cheat sheet. It is a work in progress and is not finished yet.
                    
        
                
        
            
                                
            
                
                                                
                                
            
        
    
    
            Viruses
        
                        
                                                                                    
                                                                                            Viruses are not cells  | 
                                                                                 
                                                                                            
                                                                                            They are very small (about 1/100th the size of a bacterium)  | 
                                                                                 
                                                                                            
                                                                                            They move into cells and replicate themselves using the cell's systems  | 
                                                                                 
                                                                                            
                                                                                            This causes the cells to burst making you feel ill, releasing all of the copies into the bloodstream  | 
                                                                                 
                                                                         
                             
    
    
            Bacteria
        
                        
                                                                                    
                                                                                            Small prokaryotic cells  | 
                                                                                 
                                                                                            
                                                                                            Multiply rapidly by binary fission in your body  | 
                                                                                 
                                                                                            
                                                                                            Toxins are produced which causes you to feel unwell  | 
                                                                                 
                                                                         
                             
    
    
            Fungi
        
                        
                                                                                    
                                                                                            Can be single celled or have a body made of hyphae  | 
                                                                                 
                                                                                            
                                                                                            Can produce spores which can be spread to other organisms  | 
                                                                                 
                                                                         
                             
    
    
            Protists
        
                        
                                                                                    
                                                                                            Some are parasitic meaning they use humans and snimals as their hosts  | 
                                                                                 
                                                                                            
                                                                                            All eukaryotic and most are single celled  | 
                                                                                 
                                                                         
                             
    
    
            Reducing Spread of Disease
        
                        
                                                                                    
                                                                                            Improving Hygiene  | 
                                                                                                                        Using simple hygiene measures can prevent the spread of disease. For example, doing thinhs like washing your hands thoroughly  | 
                                                                                 
                                                                                            
                                                                                            Destroying Vectors  | 
                                                                                                                        By taking precautions to remove vectors, you can prevent the disease from being passed on  | 
                                                                                 
                                                                                            
                                                                                            Isolation  | 
                                                                                                                        If you isolate someone with a communicable disease, it prevents them from passing it on to anyone else  | 
                                                                                 
                                                                                            
                                                                                            Vaccination  | 
                                                                                                                        Vaccinating people and animals from communicable disease prevents them from developing the disease and passing it on  | 
                                                                                 
                                                                         
                             
    
    
            Spread of Pathogens
        
                        
                                                                                    
                                                                                            Direct Contact  | 
                                                                                                                        touching contaminated surfaces  | 
                                                                                 
                                                                                            
                                                                                            By Water  | 
                                                                                                                        drinking or coming into contact with dirty water  | 
                                                                                 
                                                                                            
                                                                                            By Air  | 
                                                                                                                        pathogens can be carried in the air and then breathed in (droplet infection happened when sneeze droplets are inhaled)  | 
                                                                                 
                                                                         
                             
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            HIV
        
                        
                                    
                        Human Immunodeficiency Virus (HIV) can eventually lead to Acquired Immunodeficiency Syndrome (AIDS)  | 
                     
                             
                             
            
        
    
    
            Symptoms
        
                        
                                                                                    
                                                                                            - starts with flu-like illness and symptoms  | 
                                                                                 
                                                                                            
                                                                                            - if untreated, can travel to lymph nodes and attack immune system cells  | 
                                                                                 
                                                                                            
                                                                                            - can stay hidden for many years which is called AIDS  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Spread
        
                        
                                                                                    
                                                                                            - direct sexual contact (eg unprotected sex)  | 
                                                                                 
                                                                                            
                                                                                            - exchange of bodily fluids (eg blood through drug users sharing needles)  | 
                                                                                 
                                                                                            
                                                                                            - mother to child during pregnancy, birth or breast feeding  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Treatment and Prevention
        
                        
                                                                                    
                                                                                            - no cure but antiretroviral drugs used early can slow or halt the progress to AIDS  | 
                                                                                 
                                                                                            
                                                                                            - using barrier methods of contraception to prevent spread  | 
                                                                                 
                                                                                            
                                                                                            - not sharing needles or mixing blood  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Gonorrohoea
        
                        
                                                                                    
                                                                                            Introduction:  | 
                                                                                                                        - It's a sexually transmitted disease   - In 2018, it was the cause of 13% of diagnosed STDs - Bacterial infection and had the largest increase in the UK  | 
                                                                                 
                                                                                            
                                                                                            Symptoms:  | 
                                                                                                                        - Thick yellow/green discharge from genitals   - Can be asymptomatic   - Can cause infertility, pelvic pain, ectopic pregnancies, blind babies  | 
                                                                                 
                                                                                            
                                                                                            Spread:  | 
                                                                                                                        - Unprotected sex  | 
                                                                                 
                                                                                            
                                                                                            Treatment and Prevention:  | 
                                                                                                                        - Barrier methods of contraception   - can be treated with antibiotics but many strains are now becoming resistant to penicillin   - tracing of all sexual partners in essential so all individuals can be treated and/or treated  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Measles
        
                        
                                                                                    
                                                                                            - Measles is a highly contagious and potentialyl fatal viral infection.  | 
                                                                                 
                                                                                            
                                                                                            - Most often seen in children so the majority of young children are vaccinated  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Symptoms
        
                        
                                                                                    
                                                                                            - fever  | 
                                                                                 
                                                                                            
                                                                                            - red skin and a rash  | 
                                                                                 
                                                                                            
                                                                                            - can lead to blindness and brain damage in extremely severe cases  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Spread
        
                        
                                                                                    
                                                                                            - inhalation of droplets from coughs and sneezes  | 
                                                                                 
                                                                                            
                                                                                            - very infectious as these droplets can linger in the air/on surfaces  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Treatment and Prevention
        
                        
                                                                                    
                                                                                            - no treatment so infected people must be isolated to stop spread  | 
                                                                                 
                                                                                            
                                                                                            - greatly reduced in the UK due to improved living conditions and a vaccination programme for young children in place  | 
                                                                                 
                                                                         
                             
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            Salmonella
        
                        
                                                                                    
                                                                                            - Salmonella food poisoning is spread by bacteria ingested in food or food which has been prepared in unhygienic conditions  | 
                                                                                 
                                                                                            
                                                                                            - found in the gut of many different animals  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Symptoms
        
                        
                                                                                    
                                                                                            - symptoms start between 8-72 hours after eating food  | 
                                                                                 
                                                                                            
                                                                                            - generally doesn't last for more than a few days  | 
                                                                                 
                                                                                            
                                                                                            - more serious in young children and the eldery due to dehydration  | 
                                                                                 
                                                                                            
                                                                                            - fever  | 
                                                                                 
                                                                                            
                                                                                            - vomiting  | 
                                                                                 
                                                                                            
                                                                                            - diarrhoea  | 
                                                                                 
                                                                                            
                                                                                            - abdominal cramps  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Spread
        
                        
                                                                                    
                                                                                            - uncooked, contaminated food, including eggs and chicken  | 
                                                                                 
                                                                                            
                                                                                            - bacteria can remain on surfaces for some time after so other foods can also get infected  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Treatment and Prevention
        
                        
                                                                                    
                                                                                            - chickens in the UK are vaccinated for salmonella  | 
                                                                                 
                                                                                            
                                                                                            - food should be cooked thoroughly  | 
                                                                                 
                                                                                            
                                                                                            - hands should be washed before and after handling raw meat and other foods  | 
                                                                                 
                                                                                            
                                                                                            - raw meat shouldn't be washed  | 
                                                                                 
                                                                         
                             
            
        
    
    
            Tobacco Mosaic Virus
        
                        
                                                                                    
                                                                                            Introduction:   | 
                                                                                                                        - Tobacco Mosaic Virus (TMV) was the first virus to be isolated   - Widespread plant pathogen which affects ~150 species of plant  | 
                                                                                 
                                                                                            
                                                                                            Symptoms:  | 
                                                                                                                        - Mosaic pattern leaf discolouration   - Stunted growth due to lack of photosynthesis taking place  | 
                                                                                 
                                                                                            
                                                                                            Spread:  | 
                                                                                                                        - Plants in direct contact with an infected plant can also get the disease   - This particular virus can remain in the soil for ~50 years  | 
                                                                                 
                                                                                            
                                                                                            Treatment and Prevention:  | 
                                                                                                                        - No treatment currently   - Good field hygiene is the best method of control of TMV (this includes destroying any infected plants as soon as possible)   - Gentically-modified TMV-resistant crops could be grown  | 
                                                                                 
                                                                         
                             
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